What is Differin®? How does Differin&#174 work? How do I use Differin®?

What is Differin®?

Differin® (adapalene) products are proven medicines that get deep into pores to help clear the acne you have and help keep new acne from starting. The Differin® product ingredients work under the skin's surface at the source of the problem.

Which Differin® Product Is Right for Me?
Differin® products come two ways: two different strengths, one in a gel and one in a lotion (only a doctor can determine which is best for you). Whatever form you use, Differin® products help clear pimples.

  • Differin® (adapalene) Gel, 0.3% is a clear gel with a powerful formulation for those with more challenging acne. It works under the skin's surface to unclog pores and clear up pimples. Experience the powerful formulation for yourself—make an appointment and ask your doctor about Differin® Gel, 0.3%!
  • Differin® (adapalene) Lotion Pump, 0.1% is the first lotion to contain adapalene, which controls the buildup that leads to acne. It comes in a convenient, easy-to-use pump dispenser. Differin® Lotion Pump, 0.1% helps prevent the formation of new acne, and can also help get rid of acne that's already present.

Only a doctor can decide which treatment is right for you. Make an appointment and ask whether a Differin® product will work for you.

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Important Safety Information

Differin® Lotion 0.1% and Differin® Gel 0.3% are indicated for the topical treatment of acne vulgaris in patients 12 years and older. Cutaneous irritation (erythema, scaling, dryness and/or stinging/burning) has been reported in clinical studies of these products. The majority of cases were mild to moderate in severity, occurred early in treatment and decreased thereafter. Other side effects that may occur from using Differin Lotion 0.1% and Differin Gel 0.3% include dry skin, skin discomfort, pruritus, desquamation and sunburn.

Concomitant use of potentially irritating products or overexposure to sunlight or sunlamps, extreme wind or cold, may increase the potential for irritation. Use of sunscreen and protective clothing over treated areas are recommended when exposure cannot be avoided. Do not use Differin Lotion 0.1% and Differin Gel 0.3% if you are allergic to adapalene or any of the other ingredients in the product. Talk to your doctor to learn more about Differin Lotion 0.1% and Differin Gel 0.3%.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

*Insured patients could pay no more than $35 for their Differin® (adapalene) Gel, 0.3% or Differin® (adapalene) Lotion Pump, 0.1% prescription (for one tube or pump, after primary insurance and the Differin Savings at Work Card and includes a maximum benefit of $210). Restrictions may apply.

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Differin® Lotion 0.1% and Differin® Gel 0.3% are indicated for the topical treatment of acne vulgaris in patients 12 years and older. Cutaneous irritation (erythema, scaling, dryness and/or stinging/burning) has been reported in clinical studies of these products. The majority of cases were mild to moderate in severity, occurred early in treatment and decreased thereafter. Other side effects that may occur from using Differin Lotion 0.1% and Differin Gel 0.3% include dry skin, skin discomfort, pruritus, desquamation and sunburn.

Concomitant use of potentially irritating products or overexposure to sunlight or sunlamps, extreme wind or cold, may increase the potential for irritation. Use of sunscreen and protective clothing over treated areas are recommended when exposure cannot be avoided. Do not use Differin Lotion 0.1% and Differin Gel 0.3% if you are allergic to adapalene or any of the other ingredients in the product. Talk to your doctor to learn more about Differin Lotion 0.1% and Differin Gel 0.3%.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.