Retinization typically begins to subside around week 4 of daily Differin Gel treatment. Whether or not you experience retinization, remember, Differin is still working to clear and prevent acne breakouts.
Differin Gel isn’t like the other acne treatments that can’t seem to give you the results you want. So you shouldn’t try to use it in the same way. It’s a process that’s delightfully different. Delightful because it works.
Apply a thin layer of Differin all over your face once every day whether you have just a few spots or a full-on breakout. Remember, this isn’t a spot-treatment you only use when needed. Think of it like brushing your teeth: You don’t just brush the teeth with food in them, you brush them all. Every day. Because skipping days could lead to a problem. Make Differin Gel a part of your daily skincare routine to keep the problems away.
You may see some mild redness or irritation on the treated area. Don’t freak out. That’s just what dermatologists call retinization; it happens as your skin adapts to the treatment, and usually subsides after about four weeks. Differin Gel is still doing its job to reduce acne-causing clogs, so it’s important to keep using it daily. You could start to see a reduction in acne after two weeks of treatment. Keep it up, it gets better.
You should see a significant difference around the 12-week mark – clinical studies reported up to 87% acne reduction. Like any health regimen, skipping a day could lead to a setback. Continue using Differin Gel every day, even after your skin looks clearer, for increased reduction.
Most importantly, watch for positive results between week 2 and week 12. But before you achieve your best skin, you may experience a few mild side effects that subside after about week 4. Overall, Differin Gel has superior tolerability compared to other retinoid acne treatments that don’t contain adapalene. Common side effects include dryness, redness, irritation and burning/stinging. These symptoms usually peak at the 2- to 4-week mark before subsiding. Not everyone will experience these side effects, and in clinical studies, average scores were less than mild. Less common side effects include, erythema, pruritus, sunburn and acne flares, which occur in fewer than 1% of people who use Differin Gel.
It doesn’t happen to everyone, but it’s worth noting. Retinization is the adjustment period in which the skin becomes acclimated with adapalene, the retinoid in Differin Gel. During this time skin may become red and irritated. Differin Soothing Moisturizer is great to use with Differin Gel to help relieve symptoms of retinization.
Retinization occurs most frequently during the first part of treatment, when your skin is getting used to Differin Gel.Dr. Adam Friedman
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